It is unclear whether there is a link between Actonel and depression. Depression occurred in up to 6.8 percent of people taking Actonel in clinical studies. However, depression also occurred in over 6 percent of people not taking the drug. If you are taking Actonel and depression becomes a problem for you, be sure to let your healthcare provider know.
Is Depression an Actonel Side Effect?
Actonel® (
risedronate sodium) is a prescription medication approved to treat and prevent
osteoporosis and to treat Paget's disease. There are several potential
Actonel side effects. In studies,
depression occurred in up to 6.8 percent of people taking the drug. However, depression was reported in almost as many (6.2 percent) of those not taking Actonel. Therefore, it is unclear if depression is actually a side effect of Actonel. The small difference in percentages could probably be explained by chance, rather than by a real difference.
Keep in mind that just because it was unclear if Actonel caused depression in clinical studies, this does not mean that the medicine is not causing this problem in you. Clinical trials are designed to factor out many possible variables in order to understand whether a medicine works and what its possible side effects are. Clinical trials are usually limited to a specific group of people. Once the medicine is approved, a wider range of people begin taking the medicine and for longer periods of time. The bottom line is that for an individual person, it can be difficult to say whether depression is caused by Actonel or by other factors.
Actonel and Depression: Final Thoughts
If you notice any possible depression symptoms while taking Actonel, or if something "just does not seem right," you should talk to your healthcare provider. Your healthcare provider will be able to diagnose and treat the problem, and can help determine if Actonel is perhaps causing or worsening your depression.
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