Actonel Side Effects

Serious Actonel Side Effects

Some side effects with Actonel, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Throat pain, chest pain, or difficulty swallowing (which may be signs of ulcers of the esophagus)
  • Severe heartburn or heartburn that does not go away
  • Severe bone, muscle, or joint pain
  • Jaw or tooth problems
  • Anxiety
  • An irregular heart rhythm (arrhythmia)
  • Groin or thigh pain, as these might be symptoms of a rare type of broken bone that has been reported with medications like Actonel 
  • Signs of an allergic reaction, including unexplained rash, hives, itching, and unexplained swelling.

How to Minimize Actonel Side Effects on the Esophagus

In order to reduce the chances of developing serious esophageal side effects, you should follow the prescribed directions on how to take Actonel. For example:
  • Actonel should be taken on an empty stomach and with a full glass of water first thing in the morning.
  • Swallow the tablet whole. Do not suck or chew on the Actonel tablet.
  • For at least 30 minutes after taking Actonel, it is important to:


    • Remain in an upright position (sitting up or standing).
    • Wait to eat or drink. This includes mineral water, sparkling water, coffee, tea, milk, or juice. Plain water is okay.
    • Avoid taking any other oral medicines, including calcium supplements.


Final Thoughts on Actonel Side Effects

You may experience some or none of the Actonel side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect of Actonel, your healthcare provider will be able to diagnose and treat the problem.
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