Evista and Depression

Side effects can occur with the use of Evista, and depression appears to be one of them. However, in clinical studies, almost as many women who were taking a placebo also reported depression, so the risk appears to be slight. If you experience depression symptoms while taking Evista -- such as trouble sleeping or feelings of worthlessness or guilt -- tell your healthcare provider right away.

Is Depression an Evista Side Effect?

There are several possible side effects with Evista® (raloxifene hydrochloride), and depression may be one of them. In clinical studies, depression was reported in up to 6.4 percent of women taking Evista. However, almost as many (6 percent) women not taking the drug also reported being depressed. Therefore, it seems that Evista only slightly increases the risk of depression.

Evista and Depression: What Should I Look For?

Depression is extremely common in society today. Therefore, knowing the symptoms can be helpful.
Possible symptoms of depression may include:
  • Feelings of hopelessness and pessimism
  • Persistent sad, anxious, or "empty" mood
  • Decreased energy, fatigue, and feeling "slowed down"
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Difficulty concentrating, remembering, and making decisions
  • Restlessness and irritability
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss or overeating and weight gain
  • Thoughts of death or suicide and suicide attempts
  • Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain.
Keep in mind that other conditions can share similar symptoms with depression.
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Evista -- Medication Information

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