Fosamax Plus D Drug Interactions (Cont.)

Fosamax Plus D Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Fosamax Plus D is combined with any of the drugs listed above.
 
Aspirin
Both aspirin and Fosamax Plus D can be irritating to the stomach. Talk to your healthcare provider before taking aspirin if you are taking Fosamax Plus D. Of course, no other medications (including aspirin) should be taken within 30 minutes of taking Fosamax Plus D.
 
Bile Acid Sequestrants
Bile acid sequestrants can decrease the absorption of vitamin D (one of the components of Fosamax Plus D) from the digestive tract, making the medication less effective. Depending on your individual situation, your healthcare provider may recommend that you take additional vitamin D.
 
Calcium Products
Calcium binds to Fosamax Plus D in the stomach, preventing it from being absorbed in the body and making it less effective. While it is usually important for people with osteoporosis to take calcium, it should not be taken within 30 minutes of taking Fosamax Plus D.
 
Cimetidine
Cimetidine can cause your body to break down vitamin D (one of the components of Fosamax Plus D) more quickly than usual. In such cases, your healthcare provider may recommend that you take additional vitamin D.
 
Iron Supplements
Iron binds to Fosamax Plus D in the stomach, preventing it from being absorbed in the body and making it less effective. Do not take iron supplements within 30 minutes of taking Fosamax Plus D.
 
Magnesium Products
Magnesium binds to Fosamax Plus D in the stomach, preventing it from being absorbed in the body and making it less effective. Do not take magnesium supplements within 30 minutes of taking Fosamax Plus D.
(Fosamax Plus D Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;