Fosamax Plus D Side Effects

Serious Fosamax Plus D Side Effects

Some side effects with Fosamax Plus D, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Throat pain, chest pain, or difficulty swallowing (which may be signs of ulcers of the esophagus)
  • Severe heartburn or heartburn that does not go away
  • Severe bone, muscle, or joint pain
  • Jaw or tooth problems
  • Groin or thigh pain, as these might be symptoms of a rare type of broken bone that has been reported with medications like Fosamax Plus D 
  • Signs of an allergic reaction, including unexplained rash, hives, itching, and unexplained swelling.

How to Minimize Fosamax Plus D Side Effects on the Esophagus

In order to reduce the chance of developing serious esophageal-related side effects, you should follow the prescribed directions on how to take Fosamax Plus D. For example:
  • Fosamax Plus D should be taken on an empty stomach and with a full glass of water first thing in the morning.
  • Swallow the tablets whole. Do not suck or chew on the Fosamax Plus D tablets.
  • For at least 30 minutes after taking Fosamax Plus D, it is important to:
    • Remain in an upright position (either sitting up or standing). In fact, you should remain upright until you have had something to eat.
    • Wait to eat or drink. This includes mineral water, sparkling water, coffee, tea, milk, or juice. Plain water is okay.
    • Avoid taking any other oral medicine, including calcium supplements.
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