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Osteoporosis and Medications That Cause Bone Loss

The long-term use of glucocorticoids can lead to a loss of bone density and an increased number of fractures. Glucocorticoids are often used to treat a wide range of diseases, including:
Bone loss can also result from long-term treatment with:
  • Certain antiseizure drugs, such as phenytoin (Dilantin®) and barbiturates
  • Gonadotropin-releasing hormone (GnRH) drugs used to treat endometriosis
  • Excessive use of aluminum-containing antacids
  • Certain cancer treatments
  • Excessive thyroid hormone.
It is important to discuss the use of these drugs with your physician. It is also important to not stop or change your dosage on your own.

Medications Used to Prevent Osteoporosis

Various medications are available for preventing and treating osteoporosis (see Osteoporosis Medications for more information on medications used on osteoporosis prevention).
Written by/reviewed by:
Last reviewed by: Arthur Schoenstadt, MD
Last updated/reviewed:
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