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Drug Interactions

Prolia may interact with other medications (see Prolia Drug Interactions).

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to using Prolia if you have:
  • Low blood calcium (hypocalcemia)
  • Underactive parathyroid glands (hypoparathyroidism)
  • Had thyroid surgery or parathyroid surgery in the past
  • A digestive problem that causes poor absorption of vitamins and minerals
  • Had part of your intestines surgically removed
  • Severe kidney disease (and/or are on dialysis)
  • Any immune-suppressing condition, such as HIV, AIDS, or cancer
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Prolia Warnings and Precautions to learn more, including information on who should not use the drug.)

What If I Take an Overdose of Prolia?

It is unknown what exactly to expect with an overdose of this medication. At this time, there have been no reported cases of an overdose. Additionally, an overdose is unlikely, as the drug is given by a healthcare provider and a single dose consists of an entire vial (or prefilled syringe).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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