Using Reclast During Pregnancy: An Overview
) is a prescription medication used for Paget's disease of the bone and osteoporosis
. The manufacturer of the drug warns that pregnant women should not take this medication. Studies in animals have suggested that Reclast may cause problems when used during pregnancy.
Reclast and Pregnancy Category D
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents. A pregnancy Category D medicine may still be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh the risks to the unborn child.
Even though Reclast has not been studied in pregnant women, it was still given a pregnancy Category D rating, due to the many problems seen in animal studies. The following problems were seen when the drug was given to pregnant animals:
- Increased risk of miscarriages
- Increased risk of stillbirth
- Decreased survival of newborns
- Difficult or prolonged labor
- Death of the pregnant animals during labor
- Birth defects, including bone defects.